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Although multiple levels of abnormalities have been identified in innate and adaptive immunity, it remains unclear if any of the subpopulations of t cells with regulatory capacity (tregs) contribute to the induction and. However, controversy exists over the part that these cells play in determining the outcome of hepatitis b virus (hbv) and hepatitis c virus (hcv) infections, the two main causes of chronic liver inflammation worldwide. 14 claassen ma, de knegt rj, tilanus hw, janssen hl, boonstra a
Abundant numbers of regulatory t cells localize to the liver of chronic hepatitis c infected patients and limit the extent of brosis. In the past few years, we have witnessed extraordinary advances in the understanding of the functions of regulatory t (treg) cells in immunity against pathogens Fgl2 is expressed by various cells, including regulatory t cells (tregs), macrophages, epithelial cells,.
Hepatitis c viral infection persists and becomes chronic in a majority of affected individuals
Numerous factors have been described to explain how the virus manages to escape the host immune system One important escape mechanism is the increase in regulatory t cells induced by the virus In this review, we will focus on the status of regulatory t cells throughout the.
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